Safety and reactogenicity of a controlled human infection model of sand fly-transmitted cutaneous leishmaniasis

Study design

We previously reported on enabling studies, including development of a cGMP challenge strain (L. major MHOM/IL/2019/MRC-02)²⁵, development of a sand fly biting protocol²⁶ and assessments of public perceptions of the project²⁷. For this first human infection study (LEISH_Challenge;…