Aging drives cerebrovascular network remodeling and functional changes in the mouse brain

Aging drives cerebrovascular network remodeling and functional changes in the mouse brain

Animals

Animal experiments were approved by the Institutional Animal Care and Use Committee at Penn State University. Adult male and female mice were used across all age and genotype groups in this study.

For transgenic pericyte-specific experiments, PDGFRβ-Cre mice (a kind gift from the Volkhard…

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